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Design, synthesis, and in vitro antitumor activity of 6-aryloxyl substituted quinazoline derivatives

Quinazoline derivatives are a class of important antitumor drugs known as small molecule inhibitors that include epidermal growth factor receptor (EGFR) inhibitors. Based on the structure of poziotinib, a series of 6-aryloxyl substituted quinazoline derivatives were designed and synthesized. The in...

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Detalles Bibliográficos
Autores principales: FAN, Meixia, YAO, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503992/
https://www.ncbi.nlm.nih.gov/pubmed/37720611
http://dx.doi.org/10.55730/1300-0527.3373