Sex differences in brain protein expression and disease

Most complex human traits differ by sex, but we have limited insight into the underlying mechanisms. Here, we investigated the influence of biological sex on protein expression and its genetic regulation in 1,277 human brain proteomes. We found that 13.2% (1,354) of brain proteins had sex-differenti...

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Detalles Bibliográficos
Autores principales: Wingo, Aliza P., Liu, Yue, Gerasimov, Ekaterina S., Vattathil, Selina M., Liu, Jiaqi, Cutler, David J., Epstein, Michael P., Blokland, Gabriëlla A. M., Thambisetty, Madhav, Troncoso, Juan C., Duong, Duc M., Bennett, David A., Levey, Allan I., Seyfried, Nicholas T., Wingo, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504083/
https://www.ncbi.nlm.nih.gov/pubmed/37653343
http://dx.doi.org/10.1038/s41591-023-02509-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504083/
https://www.ncbi.nlm.nih.gov/pubmed/37653343
http://dx.doi.org/10.1038/s41591-023-02509-y

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