A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor

Vectors that facilitate the engineering of T cells that can better harness endogenous immunity and overcome suppressive barriers in the tumour microenvironment would help improve the safety and efficacy of T-cell therapies for more patients. Here we report the design, production and applicability, i...

Descripción completa

Detalles Bibliográficos
Autores principales: Reichenbach, Patrick, Giordano Attianese, Greta Maria Paola, Ouchen, Khaoula, Cribioli, Elisabetta, Triboulet, Melanie, Ash, Sarah, Saillard, Margaux, Vuillefroy de Silly, Romain, Coukos, George, Irving, Melita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504085/
https://www.ncbi.nlm.nih.gov/pubmed/37069267
http://dx.doi.org/10.1038/s41551-023-01013-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504085/
https://www.ncbi.nlm.nih.gov/pubmed/37069267
http://dx.doi.org/10.1038/s41551-023-01013-5

Ejemplares similares