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A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor
Vectors that facilitate the engineering of T cells that can better harness endogenous immunity and overcome suppressive barriers in the tumour microenvironment would help improve the safety and efficacy of T-cell therapies for more patients. Here we report the design, production and applicability, i...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504085/ https://www.ncbi.nlm.nih.gov/pubmed/37069267 http://dx.doi.org/10.1038/s41551-023-01013-5 |