Structure/function studies of the NAD(+)-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans reveal importance of the BRCT domain for DNA binding

Bacterial NAD(+)-dependent DNA ligases (LigAs) are enzymes involved in replication, recombination, and DNA-repair processes by catalyzing the formation of phosphodiester bonds in the backbone of DNA. These multidomain proteins exhibit four modular domains, that are highly conserved across species, w...

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Detalles Bibliográficos
Autores principales: Fernandes, Andreia, Williamson, Adele, Matias, Pedro M., Moe, Elin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504179/
https://www.ncbi.nlm.nih.gov/pubmed/37712998
http://dx.doi.org/10.1007/s00792-023-01309-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504179/
https://www.ncbi.nlm.nih.gov/pubmed/37712998
http://dx.doi.org/10.1007/s00792-023-01309-z

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