GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors

Q/R editing of the kainate receptor (KAR) subunit GluK2 radically alters recombinant KAR properties, but the effects on endogenous KARs in vivo remain largely unexplored. Here, we compared GluK2 editing-deficient mice that express ∼95% unedited GluK2(Q) to wild-type counterparts that express ∼85% ed...

Descripción completa

Detalles Bibliográficos
Autores principales: Nair, Jithin D., Wilkinson, Kevin A., Yucel, Busra P., Mulle, Christophe, Vissel, Bryce, Mellor, Jack, Henley, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504484/
https://www.ncbi.nlm.nih.gov/pubmed/37720087
http://dx.doi.org/10.1016/j.isci.2023.107708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504484/
https://www.ncbi.nlm.nih.gov/pubmed/37720087
http://dx.doi.org/10.1016/j.isci.2023.107708

Ejemplares similares