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Identification of SIRT3 as an eraser of H4K16la

Lysine lactylation (Kla) is a novel histone post-translational modification discovered in late 2019. Later, HDAC1-3, were identified as the robust Kla erasers. While the Sirtuin family proteins showed weak eraser activities toward Kla, as reported. However, the catalytic mechanisms and physiological...

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Detalles Bibliográficos
Autores principales: Fan, Zhuming, Liu, Zhiyang, Zhang, Nan, Wei, Wenyu, Cheng, Ke, Sun, Hongyan, Hao, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504495/
https://www.ncbi.nlm.nih.gov/pubmed/37720100
http://dx.doi.org/10.1016/j.isci.2023.107757