Molecular docking analysis of the oral tumor target JAK STAT 3 with oxo-azo compounds

It is of interest to identify the JAK STAT 3 signaling inhibitors to abrogate tumorigenesis in oral cancer. Hence, molecular docking was performed with known oxazole compounds (1-5) and the 3D crystal structure of JAK-1 protein from Homo sapiens (PDB ID: 3EYG). The results show that the oxo-azo deri...

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Detalles Bibliográficos
Autores principales: Karikalan, Kaviya, Veeraraghavan, Vishnu Priya, Sekaran, Surya, Rengasamy, Gayathri, Sankaran, Kavitha, Eswaramoorthy, Rajalakshmanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504500/
https://www.ncbi.nlm.nih.gov/pubmed/37720284
http://dx.doi.org/10.6026/97320630019063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504500/
https://www.ncbi.nlm.nih.gov/pubmed/37720284
http://dx.doi.org/10.6026/97320630019063

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