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Molecular docking analysis of the oral tumor target JAK STAT 3 with oxo-azo compounds

It is of interest to identify the JAK STAT 3 signaling inhibitors to abrogate tumorigenesis in oral cancer. Hence, molecular docking was performed with known oxazole compounds (1-5) and the 3D crystal structure of JAK-1 protein from Homo sapiens (PDB ID: 3EYG). The results show that the oxo-azo deri...

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Detalles Bibliográficos
Autores principales:	Karikalan, Kaviya, Veeraraghavan, Vishnu Priya, Sekaran, Surya, Rengasamy, Gayathri, Sankaran, Kavitha, Eswaramoorthy, Rajalakshmanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504500/ https://www.ncbi.nlm.nih.gov/pubmed/37720284 http://dx.doi.org/10.6026/97320630019063

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