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Molecular docking analysis of imidazole quinolines with gingipain R from Porphyromonas gingivalis

Porphyromonas gingivalis is known to produce major virulence factor, Gingipain R that could penetrate the gingivae and cause tissue destruction. In this research we aim to target the gingipain R protein with imidazole quinoline derivatives (1-6) via insilico means. Molecular docking results show, co...

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Detalles Bibliográficos
Autores principales: Reddy, Kanumuru Rahul, Rengasamy, Gayathri, Sekaran, Surya, Veeraraghavan, Vishnu Priya, Sankaran, Kavitha, Eswaramoorthy, Rajalakshmanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504515/
https://www.ncbi.nlm.nih.gov/pubmed/37720276
http://dx.doi.org/10.6026/97320630019088