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CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca(2+) oscillations and NF-κB/MAPK signaling pathways
Osteoporosis is a prevalent systemic metabolic disease in modern society, in which patients often suffer from bone loss due to over-activation of osteoclasts. Currently, amelioration of bone loss through modulation of osteoclast activity is a major therapeutic strategy. Ataxia telangiectasia mutated...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504545/ https://www.ncbi.nlm.nih.gov/pubmed/37720109 http://dx.doi.org/10.1016/j.isci.2023.107760 |