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CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca(2+) oscillations and NF-κB/MAPK signaling pathways

Osteoporosis is a prevalent systemic metabolic disease in modern society, in which patients often suffer from bone loss due to over-activation of osteoclasts. Currently, amelioration of bone loss through modulation of osteoclast activity is a major therapeutic strategy. Ataxia telangiectasia mutated...

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Detalles Bibliográficos
Autores principales: Xu, Minglian, Song, Dezhi, Xie, Xiaoxiao, Qin, Yiwu, Huang, Jian, Wang, Chaofeng, Chen, Junchun, Su, Yuangang, Xu, Jiake, Zhao, Jinmin, Liu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504545/
https://www.ncbi.nlm.nih.gov/pubmed/37720109
http://dx.doi.org/10.1016/j.isci.2023.107760