Single-cell phylogenies reveal changes in the evolutionary rate within cancer and healthy tissues

Cell lineages accumulate somatic mutations during organismal development, potentially leading to pathological states. The rate of somatic evolution within a cell population can vary due to multiple factors, including selection, a change in the mutation rate, or differences in the microenvironment. H...

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Detalles Bibliográficos
Autores principales: Borgsmüller, Nico, Valecha, Monica, Kuipers, Jack, Beerenwinkel, Niko, Posada, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504633/
https://www.ncbi.nlm.nih.gov/pubmed/37719146
http://dx.doi.org/10.1016/j.xgen.2023.100380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504633/
https://www.ncbi.nlm.nih.gov/pubmed/37719146
http://dx.doi.org/10.1016/j.xgen.2023.100380

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