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Single-cell phylogenies reveal changes in the evolutionary rate within cancer and healthy tissues
Cell lineages accumulate somatic mutations during organismal development, potentially leading to pathological states. The rate of somatic evolution within a cell population can vary due to multiple factors, including selection, a change in the mutation rate, or differences in the microenvironment. H...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504633/ https://www.ncbi.nlm.nih.gov/pubmed/37719146 http://dx.doi.org/10.1016/j.xgen.2023.100380 |