Better together: Non-additive interactions between schizophrenia risk genes

Zhang, Zhang, Forrest et al combine allele-specific open chromatin (ASoC) mapping and CRISPR-editing to evaluate the functional impact of schizophrenia risk variants on human neuronal gene expression, synaptic development, and function. In doing so, they uncover surprising non-additive effects betwe...

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Detalles Bibliográficos
Autores principales: Deans, P.J. Michael, Brennand, Kristen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504666/
https://www.ncbi.nlm.nih.gov/pubmed/37719145
http://dx.doi.org/10.1016/j.xgen.2023.100403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504666/
https://www.ncbi.nlm.nih.gov/pubmed/37719145
http://dx.doi.org/10.1016/j.xgen.2023.100403

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