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HER3 functions as an effective therapeutic target in triple negative breast cancer to potentiate the antitumor activity of gefitinib and paclitaxel

BACKGROUND: Triple negative breast cancer (TNBC) represents a significant clinical challenge. Chemotherapy remains the mainstay for a large part of TNBC patients, whereas drug resistance and tumor recurrence frequently occur. It is in urgent need to identify novel molecular targets for TNBC and deve...

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Detalles Bibliográficos
Autores principales: Lyu, Hui, Shen, Fei, Ruan, Sanbao, Tan, Congcong, Zhou, Jundong, Thor, Ann D., Liu, Bolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504712/
https://www.ncbi.nlm.nih.gov/pubmed/37716943
http://dx.doi.org/10.1186/s12935-023-03055-w