Exosomes derived from LPS-preconditioned bone marrow-derived MSC modulate macrophage plasticity to promote allograft survival via the NF-κB/NLRP3 signaling pathway

OBJECTIVES: This study investigated whether exosomes from LPS pretreated bone marrow mesenchymal stem cells (LPS pre-MSCs) could prolong skin graft survival. METHODS: The exosomes were isolated from the supernatant of MSCs pretreated with LPS. LPS pre-Exo and rapamycin were injected via the tail vei...

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Detalles Bibliográficos
Autores principales: Zhang, PeiYao, Wu, Panfeng, Khan, Umar Zeb, Zhou, Zekun, Sui, Xinlei, Li, Cheng, Dong, Kangkang, Liu, Yongjun, Qing, Liming, Tang, Juyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504750/
https://www.ncbi.nlm.nih.gov/pubmed/37716974
http://dx.doi.org/10.1186/s12951-023-02087-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504750/
https://www.ncbi.nlm.nih.gov/pubmed/37716974
http://dx.doi.org/10.1186/s12951-023-02087-8

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