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SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolism

BACKGROUND: Cancer cells are characterized by uncontrolled cell proliferation and impaired bioenergetics. Sirtuins are a family of highly conserved enzymes that play a fundamental role in energy metabolism regulation. SIRT1, in particular, drives many physiological stress responses and metabolic pat...

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Detalles Bibliográficos
Autores principales: Varghese, Benluvankar, Chianese, Ugo, Capasso, Lucia, Sian, Veronica, Bontempo, Paola, Conte, Mariarosaria, Benedetti, Rosaria, Altucci, Lucia, Carafa, Vincenzo, Nebbioso, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504761/
https://www.ncbi.nlm.nih.gov/pubmed/37715252
http://dx.doi.org/10.1186/s12967-023-04440-9