Cargando…
SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolism
BACKGROUND: Cancer cells are characterized by uncontrolled cell proliferation and impaired bioenergetics. Sirtuins are a family of highly conserved enzymes that play a fundamental role in energy metabolism regulation. SIRT1, in particular, drives many physiological stress responses and metabolic pat...
Autores principales: | Varghese, Benluvankar, Chianese, Ugo, Capasso, Lucia, Sian, Veronica, Bontempo, Paola, Conte, Mariarosaria, Benedetti, Rosaria, Altucci, Lucia, Carafa, Vincenzo, Nebbioso, Angela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504761/ https://www.ncbi.nlm.nih.gov/pubmed/37715252 http://dx.doi.org/10.1186/s12967-023-04440-9 |
Ejemplares similares
-
KDM4 Involvement in Breast Cancer and Possible Therapeutic Approaches
por: Varghese, Benluvankar, et al.
Publicado: (2021) -
Gene Transactivation and Transrepression in MYC-Driven Cancers
por: Scafuro, Marika, et al.
Publicado: (2021) -
Sirtuin Inhibitor Cambinol Induces Cell Differentiation and Differently Interferes with SIRT1 and 2 at the Substrate Binding Site
por: Giordano, Deborah, et al.
Publicado: (2023) -
Sirtuins and Disease: The Road Ahead
por: Carafa, Vincenzo, et al.
Publicado: (2012) -
Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype
por: Carafa, Vincenzo, et al.
Publicado: (2019)