Systematic characterization of a non-transgenic Aβ(1–42) amyloidosis model: synaptic plasticity and memory deficits in female and male mice

BACKGROUND: The amyloid-β (Aβ) cascade is one of the most studied theories linked to AD. In multiple models, Aβ accumulation and dyshomeostasis have shown a key role in AD onset, leading to excitatory/inhibitory imbalance, the impairments of synaptic plasticity and oscillatory activity, and memory d...

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Detalles Bibliográficos
Autores principales: Jiménez-Herrera, Raquel, Contreras, Ana, Djebari, Souhail, Mulero-Franco, Jaime, Iborra-Lázaro, Guillermo, Jeremic, Danko, Navarro-López, Juan, Jiménez-Díaz, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504764/
https://www.ncbi.nlm.nih.gov/pubmed/37716988
http://dx.doi.org/10.1186/s13293-023-00545-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504764/
https://www.ncbi.nlm.nih.gov/pubmed/37716988
http://dx.doi.org/10.1186/s13293-023-00545-4

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