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Systematic characterization of a non-transgenic Aβ(1–42) amyloidosis model: synaptic plasticity and memory deficits in female and male mice

BACKGROUND: The amyloid-β (Aβ) cascade is one of the most studied theories linked to AD. In multiple models, Aβ accumulation and dyshomeostasis have shown a key role in AD onset, leading to excitatory/inhibitory imbalance, the impairments of synaptic plasticity and oscillatory activity, and memory d...

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Detalles Bibliográficos
Autores principales:	Jiménez-Herrera, Raquel, Contreras, Ana, Djebari, Souhail, Mulero-Franco, Jaime, Iborra-Lázaro, Guillermo, Jeremic, Danko, Navarro-López, Juan, Jiménez-Díaz, Lydia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504764/ https://www.ncbi.nlm.nih.gov/pubmed/37716988 http://dx.doi.org/10.1186/s13293-023-00545-4

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