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BASIC: A Bayesian adaptive synthetic-control design for phase II clinical trials

BACKGROUND: Randomized controlled trials are considered the gold standard for evaluating experimental treatments but often require large sample sizes. Single-arm trials require smaller sample sizes but are subject to bias when using historical control data for comparative inferences. This article pr...

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Detalles Bibliográficos
Autores principales: Jiang, Liyun, Thall, Peter F, Yan, Fangrong, Kopetz, Scott, Yuan, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504821/
https://www.ncbi.nlm.nih.gov/pubmed/37313712
http://dx.doi.org/10.1177/17407745231176445