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Germline BRCA testing in pancreatic cancer: improving awareness, timing, turnaround, and uptake

Prognosis is generally poor for patients with pancreatic ductal adenocarcinoma. However, patients with germline BRCA1 or BRCA2 mutations (gBRCAm) may benefit from first-line platinum-based chemotherapy and maintenance therapy with the poly(adenosine diphosphate-ribose) polymerase inhibitor olaparib...

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Detalles Bibliográficos
Autores principales: Golan, Talia, Casolino, Raffaella, Biankin, Andrew V., Hammel, Pascal, Whitaker, Kristen D., Hall, Michael J., Riegert-Johnson, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504836/
https://www.ncbi.nlm.nih.gov/pubmed/37720496
http://dx.doi.org/10.1177/17588359231189127