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Feasibility of administration of calcitonin gene-related peptide receptor antagonist on attenuation of pain and progression in osteoarthritis

Suppressing inflammation and abnormal subchondral bone turnover is essential for reducing osteoarthritis (OA) progression and pain relief. This study focused on calcitonin gene-related peptide (CGRP), which is involved in inflammation and bone metabolism, and investigated whether a CGRP receptor ant...

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Detalles Bibliográficos
Autores principales: Nekomoto, Akinori, Nakasa, Tomoyuki, Ikuta, Yasunari, Ding, Chenyang, Miyaki, Shigeru, Adachi, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505157/
https://www.ncbi.nlm.nih.gov/pubmed/37717108
http://dx.doi.org/10.1038/s41598-023-42673-2