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Genome-wide promoter responses to CRISPR perturbations of regulators reveal regulatory networks in Escherichia coli
Elucidating genome-scale regulatory networks requires a comprehensive collection of gene expression profiles, yet measuring gene expression responses for every transcription factor (TF)-gene pair in living prokaryotic cells remains challenging. Here, we develop pooled promoter responses to TF pertur...
Autores principales: | Han, Yichao, Li, Wanji, Filko, Alden, Li, Jingyao, Zhang, Fuzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505187/ https://www.ncbi.nlm.nih.gov/pubmed/37717013 http://dx.doi.org/10.1038/s41467-023-41572-4 |
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