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Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice
Microglia, the innate immune cells of the central nervous system, actively participate in brain development by supporting neuronal maturation and refining synaptic connections. These cells are emerging as highly metabolically flexible, able to oxidize different energetic substrates to meet their ene...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505217/ https://www.ncbi.nlm.nih.gov/pubmed/37717033 http://dx.doi.org/10.1038/s41467-023-41502-4 |