Cargando…

CRNDE mediated hnRNPA2B1 stability facilitates nuclear export and translation of KRAS in colorectal cancer

Development of colorectal cancer (CRC) involves activation of Kirsten rat sarcoma viral oncogene homolog (KRAS) signaling. However, the post-transcriptional regulation of KRAS has yet to be fully characterized. Here, we found that the colorectal neoplasia differentially expressed (CRNDE)/heterogeneo...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Ya, Zou, Renrui, Gu, Quan, Wang, Xinyue, Zhang, Junying, Ma, Rong, Wang, Ting, Wu, Jianzhong, Feng, Jifeng, Zhang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505224/
https://www.ncbi.nlm.nih.gov/pubmed/37716979
http://dx.doi.org/10.1038/s41419-023-06137-9