Insulin resistance, kidney outcomes and effects of the endothelin receptor antagonist atrasentan in patients with type 2 diabetes and chronic kidney disease

BACKGROUND: Insulin resistance (IR) is a pathophysiologic hallmark of type 2 diabetes and associated with the presence of chronic kidney disease (CKD). Experimental studies suggest that endothelin-1 increases IR. We assessed the association between IR and cardio-renal outcomes and the effect of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Smeijer, J. David, Kohan, Donald E., Rossing, Peter, Correa-Rotter, Ricardo, Liew, Adrian, Tang, Sydney C.W., de Zeeuw, Dick, Gansevoort, Ron T., Ju, Wenjun, Lambers Heerspink, Hiddo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505320/
https://www.ncbi.nlm.nih.gov/pubmed/37716952
http://dx.doi.org/10.1186/s12933-023-01964-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505320/
https://www.ncbi.nlm.nih.gov/pubmed/37716952
http://dx.doi.org/10.1186/s12933-023-01964-8

Ejemplares similares