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NAD(+) exhaustion by CD38 upregulation contributes to blood pressure elevation and vascular damage in hypertension

Hypertension is characterized by endothelial dysfunction and arterial stiffness, which contribute to the pathogenesis of atherosclerotic cardiovascular diseases. Nicotinamide adenine dinucleotide (NAD(+)) is an indispensable cofactor in all living cells that is involved in fundamental biological pro...

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Detalles Bibliográficos
Autores principales: Qiu, Yumin, Xu, Shiyue, Chen, Xi, Wu, Xing, Zhou, Zhe, Zhang, Jianning, Tu, Qiang, Dong, Bing, Liu, Zhefu, He, Jiang, Zhang, Xiaoyu, Liu, Shuangshuang, Su, Chen, Huang, Hui, Xia, Wenhao, Tao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505611/
https://www.ncbi.nlm.nih.gov/pubmed/37718359
http://dx.doi.org/10.1038/s41392-023-01577-3