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In-vitro and computational analysis of Urolithin-A for anti-inflammatory activity on Cyclooxygenase 2 (COX-2)

Cyclooxygenase 2 (COX-2) participates in the inflammation process by converting arachidonic acid into prostaglandin G2 which increases inflammation, pain and fever. COX-2 has an active site and a heme pocket and blocking these sites stops the inflammation. Urolithin A is metabolite of ellagitannin p...

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Detalles Bibliográficos
Autores principales: Revankar, Archana G., Bagewadi, Zabin K., Shaikh, Ibrahim Ahmed, Mannasaheb, Basheerahmed Abdulaziz, Ghoneim, Mohammed M., Khan, Aejaz Abdullatif, Asdaq, Syed Mohammed Basheeruddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505678/
https://www.ncbi.nlm.nih.gov/pubmed/37727526
http://dx.doi.org/10.1016/j.sjbs.2023.103804