Cargando…

Safety Assessment of a Nucleoside Analogue FNC (2’-deoxy-2’-β-fluoro-4’-azidocytidine ) in Balb/c Mice: Acute Toxicity Study

OBJECTIVES: The present study aimed to provide an insight into the acute toxicity of a novel fluorinated nucleoside analogue (FNA), FNC (Azvudine or2’-deoxy-2’-β-fluoro-4’-azidocytidine). FNC showed potent anti-viral and anti-cancer activities and approved drug for high-load HIV patients, despite, i...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Naveen, Delu, Vikram, Shukla, Alok, Singh, Rishi Kant, Ulasov, Ilya, Fayzullina, Daria, Kuma, Sandeep, Patel, Anand Kumar, Yadav, Lokesh, Tiwari, Ruchi, Rachana, Kumari, Mohanta, Shivashish Priyadarshi, Kumar, Sanjay, Kaushalendra, Kaushalendra, Acharya, Arbind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505880/
https://www.ncbi.nlm.nih.gov/pubmed/37378948
http://dx.doi.org/10.31557/APJCP.2023.24.6.2157