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microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes

Slower translation rates reduce protein misfolding. Such reductions in speed can be mediated by the presence of non‐optimal codons, which allow time for proper folding to occur. Although this phenomenon is conserved from bacteria to humans, it is not known whether there are additional eukaryote‐spec...

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Detalles Bibliográficos
Autores principales: Sako, Hiroaki, Youssef, Mohieldin, Elisseeva, Olga, Akimoto, Takayuki, Suzuki, Katsuhiko, Ushida, Takashi, Yamamoto, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505912/
https://www.ncbi.nlm.nih.gov/pubmed/37492926
http://dx.doi.org/10.15252/embj.2022112469