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ADPGK‐AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth

Long noncoding RNAs (lncRNAs) influence the transcription of gene networks in many cell types, but their role in tumor‐associated macrophages (TAMs) is still largely unknown. We found that the lncRNA ADPGK‐AS1 was substantially upregulated in artificially induced M2‐like human macrophages, macrophag...

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Detalles Bibliográficos
Autores principales: Karger, Annika, Mansouri, Siavash, Leisegang, Matthias S, Weigert, Andreas, Günther, Stefan, Kuenne, Carsten, Wittig, Ilka, Zukunft, Sven, Klatt, Stephan, Aliraj, Blerina, Klotz, Laura V, Winter, Hauke, Mahavadi, Poornima, Fleming, Ingrid, Ruppert, Clemens, Witte, Biruta, Alkoudmani, Ibrahim, Gattenlöhner, Stefan, Grimminger, Friedrich, Seeger, Werner, Pullamsetti, Soni Savai, Savai, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505917/
https://www.ncbi.nlm.nih.gov/pubmed/37545364
http://dx.doi.org/10.15252/embj.2022111620