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Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression

Replication of the mitochondrial genome and expression of the genes it encodes both depend on a sufficient supply of nucleotides to mitochondria. Accordingly, dysregulated nucleotide metabolism not only destabilises the mitochondrial genome, but also affects its transcription. Here, we report that a...

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Detalles Bibliográficos
Autores principales: Grotehans, Nils, McGarry, Lynn, Nolte, Hendrik, Xavier, Vanessa, Kroker, Moritz, Narbona‐Pérez, Álvaro Jesús, Deshwal, Soni, Giavalisco, Patrick, Langer, Thomas, MacVicar, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505918/
https://www.ncbi.nlm.nih.gov/pubmed/37439264
http://dx.doi.org/10.15252/embj.2022113256