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Combining single-cell sequencing and spatial transcriptome sequencing to identify exosome-related features of glioblastoma and constructing a prognostic model to identify BARD1 as a potential therapeutic target for GBM patients

BACKGROUND: Glioblastoma (GBM) is a malignant primary brain tumor. This study focused on exploring the exosome-related features of glioblastoma to better understand its cellular composition and molecular characteristics. METHODS: Single-cell RNA sequencing (scRNA-seq) and spatial transcriptome RNA s...

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Detalles Bibliográficos
Autores principales: Zhao, Songyun, Wang, Qi, Ni, Kaixiang, Zhang, Pengpeng, Liu, Yuan, Xie, Jiaheng, Ji, Wei, Cheng, Chao, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505933/
https://www.ncbi.nlm.nih.gov/pubmed/37727789
http://dx.doi.org/10.3389/fimmu.2023.1263329