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Peripheral neuropathy associated with monomethyl auristatin E-based antibody-drug conjugates

Since the successful approval of gemtuzumab ozogamicin, antibody-drug conjugates (ADCs) have emerged as a pivotal category of targeted therapies for cancer. Among these ADCs, the use of monomethyl auristatin E (MMAE) as a payload is prevalent in the development of ADC drugs, which has significantly...

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Detalles Bibliográficos
Autores principales: Fu, Zhiwen, Gao, Chen, Wu, Tingting, Wang, Lulu, Li, Shijun, Zhang, Yu, Shi, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505985/
https://www.ncbi.nlm.nih.gov/pubmed/37727735
http://dx.doi.org/10.1016/j.isci.2023.107778