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Smooth muscle cell-targeted RNA ligand promotes accelerated reendothelialization in a swine peripheral injury model

The local delivery of antiproliferative agents to inhibit neointimal growth is not specific to vascular smooth muscle cells (VSMC) and delays reendothelialization and vascular healing. This investigation was intended to evaluate the effect of luminal delivery of a VSMC-specific aptamer on endothelia...

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Detalles Bibliográficos
Autores principales: Lei, Beilei, Liu, Linda B., Stokes, Lauren, Giangrande, Paloma H., Miller, Francis J., Yazdani, Saami K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506064/
https://www.ncbi.nlm.nih.gov/pubmed/37727270
http://dx.doi.org/10.1016/j.omtn.2023.08.025