Termination codon readthrough of NNAT mRNA regulates calcium-mediated neuronal differentiation

Termination codon readthrough (TCR) is a process in which ribosomes continue to translate an mRNA beyond a stop codon generating a C-terminally extended protein isoform. Here, we demonstrate TCR in mammalian NNAT mRNA, which encodes NNAT, a proteolipid important for neuronal differentiation. This is...

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Detalles Bibliográficos
Autores principales: Pandit, Madhuparna, Akhtar, Md Noor, Sundaram, Susinder, Sahoo, Sarthak, Manjunath, Lekha E., Eswarappa, Sandeep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506107/
https://www.ncbi.nlm.nih.gov/pubmed/37611826
http://dx.doi.org/10.1016/j.jbc.2023.105184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506107/
https://www.ncbi.nlm.nih.gov/pubmed/37611826
http://dx.doi.org/10.1016/j.jbc.2023.105184

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