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Termination codon readthrough of NNAT mRNA regulates calcium-mediated neuronal differentiation
Termination codon readthrough (TCR) is a process in which ribosomes continue to translate an mRNA beyond a stop codon generating a C-terminally extended protein isoform. Here, we demonstrate TCR in mammalian NNAT mRNA, which encodes NNAT, a proteolipid important for neuronal differentiation. This is...
Autores principales: | Pandit, Madhuparna, Akhtar, Md Noor, Sundaram, Susinder, Sahoo, Sarthak, Manjunath, Lekha E., Eswarappa, Sandeep M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506107/ https://www.ncbi.nlm.nih.gov/pubmed/37611826 http://dx.doi.org/10.1016/j.jbc.2023.105184 |
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