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ERα promotes SUMO1 transcription by binding with the ERE and enhances SUMO1-mediated protein SUMOylation in breast cancer

BACKGROUND: Estrogen plays a crucial role in the tumorigenesis of breast cancer (BC), and epigenetic modification by SUMOylation is essential for cancer development. However, the mechanism underlying estrogen’s actions on protein SUMOylation and its effect on BC development are still incompletely un...

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Detalles Bibliográficos
Autores principales: Wang, Quhui, Zhang, Nannan, Yang, Xiaobing, Feng, Shichun, Wang, Feiran, Zhang, Wei, He, Zhixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506115/
https://www.ncbi.nlm.nih.gov/pubmed/37727335
http://dx.doi.org/10.21037/gs-23-39