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Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract

BACKGROUND: Arginase-1 (ARG1) promotes collagen synthesis and cell proliferation. ARG1 is highly expressed in various tumour cells. The mechanisms of ARG1 in epithelial-to-mesenchymal transition (EMT)-associated cataracts were studied herein. METHODS: C57BL/6 mice, a human lens epithelial cell line...

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Detalles Bibliográficos
Autores principales: Li, Qingyu, Wang, Yuchuan, Shi, Luoluo, Wang, Qing, Yang, Guang, Deng, Lin, Tian, Ye, Hua, Xia, Yuan, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506332/
https://www.ncbi.nlm.nih.gov/pubmed/37723490
http://dx.doi.org/10.1186/s12964-023-01210-4