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Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract
BACKGROUND: Arginase-1 (ARG1) promotes collagen synthesis and cell proliferation. ARG1 is highly expressed in various tumour cells. The mechanisms of ARG1 in epithelial-to-mesenchymal transition (EMT)-associated cataracts were studied herein. METHODS: C57BL/6 mice, a human lens epithelial cell line...
Autores principales: | Li, Qingyu, Wang, Yuchuan, Shi, Luoluo, Wang, Qing, Yang, Guang, Deng, Lin, Tian, Ye, Hua, Xia, Yuan, Xiaoyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506332/ https://www.ncbi.nlm.nih.gov/pubmed/37723490 http://dx.doi.org/10.1186/s12964-023-01210-4 |
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