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Immobilised-enzyme microreactors for the identification and synthesis of conjugated drug metabolites

The study of naturally circulating drug metabolites has been a focus of interest, since these metabolites may have different therapeutic and toxicological effects compared to the parent drug. The synthesis of metabolites outside of the human body is vital in order to conduct studies into the pharmac...

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Detalles Bibliográficos
Autores principales: Doyle, Bradley, Madden, Leigh A., Pamme, Nicole, Jones, Huw S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506384/
https://www.ncbi.nlm.nih.gov/pubmed/37727313
http://dx.doi.org/10.1039/d3ra03742h