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Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Kidney formation and nephrogenesis are controlled by precise spatiotemporal gene expression programs, which are coordinately regulated by cell-cycle, cell type-specific transcription factors and epigenetic/chromatin regulators. However, the roles of epigenetic/chromatin regulators in kidney developm...

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Detalles Bibliográficos
Autores principales: Xu, Jinshu, Zhou, Xianxiao, Zhang, Ting, Zhang, Bin, Xu, Pin-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506413/
https://www.ncbi.nlm.nih.gov/pubmed/37727504
http://dx.doi.org/10.3389/fcell.2023.1233317