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Disruption of the microbiota-gut-brain axis is a defining characteristic of the α-Gal A (-/0) mouse model of Fabry disease

Fabry disease (FD) is an X-linked metabolic disease caused by a deficiency in α-galactosidase A (α-Gal A) activity. This causes accumulation of glycosphingolipids, especially globotriaosylceramide (Gb3), in different cells and organs. Neuropathic pain and gastrointestinal (GI) symptoms, such as abdo...

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Detalles Bibliográficos
Autores principales: Delprete, C., Rimondini Giorgini, R., Lucarini, E., Bastiaanssen, T.F.S., Scicchitano, D., Interino, N., Formaggio, F., Uhlig, F., Ghelardini, C., Hyland, N.P., Cryan, J.F., Liguori, R., Candela, M., Fiori, J., Turroni, S., Di Cesare Mannelli, L., Caprini, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506438/
https://www.ncbi.nlm.nih.gov/pubmed/37712629
http://dx.doi.org/10.1080/19490976.2023.2256045