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Disruption of the microbiota-gut-brain axis is a defining characteristic of the α-Gal A (-/0) mouse model of Fabry disease
Fabry disease (FD) is an X-linked metabolic disease caused by a deficiency in α-galactosidase A (α-Gal A) activity. This causes accumulation of glycosphingolipids, especially globotriaosylceramide (Gb3), in different cells and organs. Neuropathic pain and gastrointestinal (GI) symptoms, such as abdo...
Autores principales: | Delprete, C., Rimondini Giorgini, R., Lucarini, E., Bastiaanssen, T.F.S., Scicchitano, D., Interino, N., Formaggio, F., Uhlig, F., Ghelardini, C., Hyland, N.P., Cryan, J.F., Liguori, R., Candela, M., Fiori, J., Turroni, S., Di Cesare Mannelli, L., Caprini, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506438/ https://www.ncbi.nlm.nih.gov/pubmed/37712629 http://dx.doi.org/10.1080/19490976.2023.2256045 |
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