Cleavage of 14-3-3ε by the enteroviral 3C protease dampens RIG-I-mediated antiviral signaling

Viruses have evolved diverse strategies to evade the host innate immune response and promote infection. The retinoic acid-inducible gene I (RIG-I)-like receptors RIG-I and MDA5 are antiviral factors that sense viral RNA and trigger downstream signal via mitochondrial antiviral-signaling protein (MAV...

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Detalles Bibliográficos
Autores principales: Andrews, Daniel D. T., Vlok, Marli, Akbari Bani, Dorssa, Hay, Brenna N., Mohamud, Yasir, Foster, Leonard J., Luo, Honglin, Overall, Christopher M., Jan, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506458/
https://www.ncbi.nlm.nih.gov/pubmed/37555661
http://dx.doi.org/10.1128/jvi.00604-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506458/
https://www.ncbi.nlm.nih.gov/pubmed/37555661
http://dx.doi.org/10.1128/jvi.00604-23

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