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TLR2 is non-redundant in the population and subpopulation responses to Mycobacterium tuberculosis in macrophages and in vivo

Tuberculosis (TB), caused by the pathogenic bacterium Mycobacterium tuberculosis (Mtb), is a global health threat. Targeting host pathways that modulate protective or harmful components of inflammation has been proposed as a therapeutic strategy that could aid sterilization or mitigate TB-associated...

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Detalles Bibliográficos
Autores principales: Jani, Charul, Solomon, Sydney L., Peters, Joshua M., Pringle, Stephanie C., Hinman, Amelia E., Boucau, Julie, Bryson, Bryan D., Barczak, Amy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506474/
https://www.ncbi.nlm.nih.gov/pubmed/37439558
http://dx.doi.org/10.1128/msystems.00052-23