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Fitness effects of mutations to SARS-CoV-2 proteins

Knowledge of the fitness effects of mutations to SARS-CoV-2 can inform assessment of new variants, design of therapeutics resistant to escape, and understanding of the functions of viral proteins. However, experimentally measuring effects of mutations is challenging: we lack tractable lab assays for...

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Detalles Bibliográficos
Autores principales: Bloom, Jesse D, Neher, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506532/
https://www.ncbi.nlm.nih.gov/pubmed/37727875
http://dx.doi.org/10.1093/ve/vead055