miR-200a-3p overexpression alleviates diabetic cardiomyopathy injury in mice by regulating autophagy through the FOXO3/Mst1/Sirt3/AMPK axis

OBJECTIVE: Hyperglycemia and insulin resistance or deficiency are characteristic features of diabetes. Diabetes is accompanied by cardiomyocyte hypertrophy, fibrosis and ventricular remodeling, and eventually heart failure. In this study, we established a diabetic cardiomyopathy (DCM) mouse model to...

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Detalles Bibliográficos
Autores principales: You, Penghua, Chen, Haichao, Han, Wenqi, Deng, Jizhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506579/
https://www.ncbi.nlm.nih.gov/pubmed/37727684
http://dx.doi.org/10.7717/peerj.15840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506579/
https://www.ncbi.nlm.nih.gov/pubmed/37727684
http://dx.doi.org/10.7717/peerj.15840

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