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miR-200a-3p overexpression alleviates diabetic cardiomyopathy injury in mice by regulating autophagy through the FOXO3/Mst1/Sirt3/AMPK axis

OBJECTIVE: Hyperglycemia and insulin resistance or deficiency are characteristic features of diabetes. Diabetes is accompanied by cardiomyocyte hypertrophy, fibrosis and ventricular remodeling, and eventually heart failure. In this study, we established a diabetic cardiomyopathy (DCM) mouse model to...

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Detalles Bibliográficos
Autores principales:	You, Penghua, Chen, Haichao, Han, Wenqi, Deng, Jizhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2023
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506579/ https://www.ncbi.nlm.nih.gov/pubmed/37727684 http://dx.doi.org/10.7717/peerj.15840

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